Antioxidant and Anti-fatigue Properties of Malus spectabilis Fruit Polysaccharides in Mice

Authors

• Zhilin WEN, Department of Sports , Guilin University of Electronic Technology , Guilin 541004 , China
• Ming LI, Key Laboratory of Nutrition , Metabolism and Food Safety , University of Chinese Academy of Sciences , Beijing 101408 , ChinaFollow

Corresponding Author(s)

李明（1974—），男，博士，教授，博士研究生导师，主要从事食品科学及生物技术研究。E-mail：shiyoo01@163.com

Abstract

[Objective ] This study aimed to explore the antioxidant and anti-fatigue properties of Malus spectabilis fruit polysaccharides (MPPs ) and analyze the structure-activity relationships.[Method ] Two types of MPPs were prepared via acidic (AC-MPC ) and alkaline (AL-MPC ) extraction methods.The polysaccharide composition was identified by high-performance anion-exchange chromatography (HPAEC ).The changes in mouse body mass,serum biochemical indicators,and exhaustive swimming time were measured to assess the in vivo antioxidant and anti-fatigue effects of MPPs.[Result ] Galacturonic acid was the main component in both types of MMPs,while AL-MPC had higher mass fraction of total polysaccharides.The in vivo experiments demonstrated that both types of MMPs possessed significant antioxidant and anti-fatigue activities.In particular,AL-MPC showcased better performance.Compared with the control group,high-dose AL-MPC substantially enhanced the antioxidant enzyme activities and reduced the malondialdehyde (MDA ) level in the mouse liver.In addition,AL-MPC significantly prolonged the exhaustive swimming time of mice and reduced the blood urea nitrogen (BUN ),lactic acid (LA),and lactate dehydrogenase (LDH ) levels.[Conclusion ] MMPs have significant antioxidant and anti-fatigue activities.Especially,AL-MPC exhibits more excellent bioactivity due to its unique structural features.This study provides a scientific basis and potential raw materials for the value-added utilization of Malus spectabilis fruits and the development of functional foods.

Publication Date

1-15-2026

First Page

121

Last Page

129

DOI

10.12441/spyswjs.20241012001

Recommended Citation

WEN, Zhilin and LI, Ming (2026) "Antioxidant and Anti-fatigue Properties of Malus spectabilis Fruit Polysaccharides in Mice," Journal of Food Science and Biotechnology: Vol. 45: Iss. 1, Article 12.
DOI: 10.12441/spyswjs.20241012001
Available at: https://spsw.spyswjs.cnjournals.com/journal/vol45/iss1/12

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